Get ready, get set, get wet

Fluconazole for the prevention of fungal infections: get ready, get set, caution.

Get Happy, Get Rich

The world’s poor, whether they live in dangerous urban slums or in the remote countryside, are often in dire need of food, clean water, and basic medications. So it might appear misguided to argue that mental health should be a primary rather than secondary concern in developing countries. But the reality is that mental health is not just a First World problem: disorders such as depression are ...

Get Ready for Agile Methods, with Care

F aced with the conflicting pressures of accelerated product development and users who demand that increasingly vital systems be made ever more dependable, software development has been thrown into turmoil. Traditionalists advocate using extensive planning, codified processes, and rigorous reuse to make development an efficient and predictable activity that gradually matures toward perfection. ...

Get Syk and get cycling

Overenthusiastic repair of damaged blood vessels could cause a fatal blockage. Sedding et al. (page 2801) report that the normal repair-restricting function of factor VII activating protease (FSAP) is disrupted by a common mutation. People carrying the mutation might thus be more at risk of vessel narrowing. Approximately 5% of the population carries an FSAP polymorphism linked to cardiovascula...

Mitosis: Don't get mad, get even

The 'mitotic spindle checkpoint' ensures that, before a cell exits from mitosis, all of its chromosomes are aligned on the spindle to form the metaphase plate. Mad2 is an essential component of this checkpoint system and it binds specifically to unattached kinetochores.